CTICasesInhaled Cosmetic Talcosis
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Imaging findings
Chest CT reveals diffuse, poorly defined, smudgy centrilobular ground-glass nodules distributed throughout both lungs without a clear zonal predominance, mimicking hypersensitivity pneumonitis.
Key takeaways
Inhaled talcosis is an occupational or environmental exposure caused by chronic inhalation of cosmetic talcum powder (hydrous magnesium silicate), which can lead to foreign body granulomatous inflammation. Radiologically, it often manifests as diffuse, poorly defined centrilobular nodules or progressive conglomerate masses with high attenuation, and clinical history is critical to distinguish it from other interstitial diseases like hypersensitivity pneumonitis.
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