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Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis (LCH)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Temporal bone CT demonstrates an osteolytic, destructive mass involving the left temporal bone. Chest CT shows multiple small, cavitary nodules bilaterally throughout the lungs.

Key takeaways

Langerhans cell histiocytosis (LCH) can occur in non-smoking patients and present with multisystem involvement. While the skeleton, including the temporal bone, is a common site of extra-pulmonary involvement presenting with pain or hearing loss, the classic thoracic findings of small cavitating nodules should prompt consideration of this clonal neoplastic disorder.

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