CTICasesEBV-Positive Post-Transplant Lymphoproliferative Disorder
Imaging findings
A kidney-pancreas transplant patient developed abdominal masses raising concern for PTLD, along with well-defined, smooth-marginated pulmonary nodules. CT confirms abdominal masses and lung nodules of a lymphoid appearance. Radiographs show the subtle nodules as well.
Key takeaways
Post-transplant lymphoproliferative disorder can present with well-defined smooth pulmonary nodules that overlap with fungal infection, nocardia, and metastases, and lung involvement may occur with or without disease elsewhere. PTLD is usually EBV-positive, as it was in this biopsy-proven case, and its lymphoid-appearing nodules should be considered in the differential for pulmonary nodules in a solid-organ transplant recipient.
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See all cases from January 21, 2021 →