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Lupus Flare Hemopericardium

Imaging findings

Chest CT shows a rapidly enlarging, intermediate-attenuation (40 HU) pericardial effusion causing tamponade. The patient had a history of lupus and presented with an INR >10 due to lupus anticoagulant. Pericardiocentesis yielded bloody fluid.

Key takeaways

Bloody pericardial effusions in lupus patients can occur due to the combination of lupus serositis/pericarditis and coagulopathy (e.g., elevated INR from warfarin or lupus anticoagulants), presenting with acute tamponade.

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