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Recurrent Squamous Cell Carcinoma in Respiratory Papillomatosis with Rib Invasion

Recurrent Squamous Cell Carcinoma in Respiratory Papillomatosis with Rib Invasion▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Severe volume loss in the right hemithorax with a large mass in the right lung, showing consolidation and fluid levels. A mass lesion consistent with papilloma is observed in the trachea, causing obstruction. MRI reveals a large necrotic mass with fluid pockets and recurrent squamous cell carcinoma invading the rib.

Key takeaways

Recurrent respiratory papillomatosis carries a risk of malignant transformation to squamous cell carcinoma. This can manifest as extensive intrathoracic disease, including large obstructing tracheal masses, distal lung complications, and local invasion of adjacent structures such as the ribs.

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