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Expiratory-Phase Contrast-Enhanced CT Accentuation of Mosaic Perfusion in Pulmonary Hypertension

Imaging findings

CT chest imaging demonstrates a dilated main pulmonary artery and a prominent mosaic perfusion pattern, characterized by geographic zones of relative oligemia and lucency. An expiratory-phase CT pulmonary angiogram significantly accentuates the density differences across the lung parenchyma.

Key takeaways

Mosaic perfusion is a classic sign of pulmonary hypertension or chronic thromboembolic disease, representing regional variations in lung perfusion due to vascular obstruction or pruning. Performing CT imaging in the expiratory phase can dramatically accentuate these regional parenchymal density differences, facilitating the detection of subtle pulmonary vascular disease.

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