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Lymphangiomatosis with Dystrophic Calcification

Imaging findings

A patient with lymphangiomatosis presented with a lower mediastinal and spinal mass with associated rib problems. CT revealed a low-attenuation posterior mediastinal mass containing multiple calcifications that initially appeared like phleboliths. Further imaging confirmed multiple lymphangiomas in the spleen, vertebral bodies, retroperitoneum, and throughout the abdomen.

Key takeaways

Lymphangiomatosis is a rare lymphatic malformation characterized by multiple discrete lymphatic masses (lymphangiomas) that can affect various organs. Dystrophic calcification, which can mimic phleboliths, is a known feature of lymphangiomas and does not necessarily indicate a co-existing hemangioma component. Lymphangiectasia, in contrast, involves congenital dilation of lymphatics, leading to septal thickening and chylous effusions, but typically not discrete masses.

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