CTICasesCardiac light chain amyloidosis
Imaging findings
Cardiac MRI demonstrates diffuse, global subendocardial delayed enhancement of both the left and right ventricles, thickening and enhancement of the interatrial septum, and enlargement of the atria with preserved ventricular systolic function. There is also complete nulling of the blood pool on inversion recovery scout.
Key takeaways
Cardiac amyloidosis, specifically light chain amyloidosis, is characterized by diffuse subendocardial late gadolinium enhancement that does not follow a coronary artery distribution. A characteristic finding is early nulling of the myocardium relative to the blood pool on inversion recovery imaging due to altered gadolinium kinetics.
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