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Flipped Pacemaker Generator (Pre-Twiddler Syndrome)

Imaging findings

Serial chest radiographs three months apart demonstrate a 180-degree rotation/flip of the pacemaker generator along the vertical/z-axis inside its subcutaneous pocket, leading to wrapping of the pacing leads around the generator.

Key takeaways

Pacemaker or ICD generator rotation within the subcutaneous pocket (flipped generator) can occur in patients with large pockets or mobile subcutaneous tissue. This is a precursor to Twiddler's syndrome. Generator rotation wraps the leads around the device, risking lead tension, dislodgement, or malfunction.

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