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Fibrosing Mediastinitis

Imaging findings

CT chest shows a calcified mediastinal/hilar mass obstructing the left upper lobe bronchus and pulmonary arteries, associated with severe pulmonary hypertension and right ventricular hypertrophy.

Key takeaways

Fibrosing mediastinitis is a rare, benign, but clinically devastating condition characterized by dense fibrotic tissue in the mediastinum. It is typically a late, abnormal immunologic reaction to histoplasmosis or tuberculosis, causing obstruction of the central bronchi and pulmonary vessels.

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