CTICasesTalc Embolization
Imaging findings
CT chest shows multiple, hyperdense filling defects within the right atrium, right ventricle, and bilateral pulmonary arteries, with associated wedge-shaped peripheral consolidations (lung infarcts). The patient is an IV drug user.
Key takeaways
Intravenous injection of crushed oral tablets (which contain talc, starch, or microcrystalline cellulose as fillers) causes talc embolization. These insoluble particles accumulate in the right heart chambers and pulmonary arteries, leading to vascular occlusion, pulmonary infarction, and endocarditis.
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