CTICasesSubaortic Membrane (Subvalvular Aortic Stenosis)
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Imaging findings
A full study for TAVI planning showed a shelf of soft tissue located near the left ventricular outflow tract, below the aortic valve leaflets, distinctly separate from the valve itself. This subaortic membrane was responsible for a significant left ventricular outflow tract gradient, with an opening area less than one centimeter squared, while the aortic valve opening area was not severely restricted. The patient had Down syndrome.
Key takeaways
A subaortic membrane is a congenital anomaly presenting as a shelf of soft tissue in the left ventricular outflow tract, causing subvalvular aortic stenosis. It can be the primary cause of an outflow tract gradient, distinguishing it from valvular aortic stenosis and influencing treatment, often requiring surgical resection rather than TAVI. This condition is sometimes associated with Down syndrome.
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