CTICasesCarcinoid Heart Disease
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Imaging findings
Non-gated CT pulmonary angiogram shows enlargement of the right ventricle and right atrium, contrast reflux into the inferior vena cava, and distinct thickening of the tricuspid valve leaflets. Abdominal CT images demonstrate hypervascular liver metastases and a mesenteric mass, consistent with metastatic carcinoid tumor, and echocardiography confirms severe tricuspid regurgitation with immobile leaflets.
Key takeaways
Carcinoid heart disease is a paraneoplastic complication of metastatic neuroendocrine tumors, caused by circulating vasoactive substances such as serotonin that damage the endocardium. It characteristically affects the right-sided chambers and valves, leading to fibrous plaque-like thickening, tricuspid regurgitation, and right-sided heart failure.
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