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Pulmonary Coccidioidomycosis

Imaging findings

Chest CT imaging demonstrates a solitary pulmonary nodule or mass with patent airways coursing through it, accompanied by an enlarged ipsilateral paratracheal lymph node. Imaging of a second patient shows a dominant nodule surrounded by smaller satellite nodules tracking along the bronchovascular bundle, mimicking histoplasmosis.

Key takeaways

Coccidioidomycosis (Valley Fever) is endemic to the southwestern United States and should be suspected in patients presenting with nodules, lymphadenopathy, and systemic symptoms like conjunctivitis or anterior uveitis, even after brief travel exposure. A single weekend trip or passing through an endemic region is sufficient for infection. While conjunctivitis is a well-known systemic manifestation of Valley Fever, anterior uveitis is a rarer extra-pulmonary complication.

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