CTICasesPrimary and Reactivated Cavitary Histoplasmosis (Histoplasmoma)
Imaging findings
Initial chest radiograph and CT in a symptomatic patient demonstrate dense consolidation, nodules, and a pleural effusion, which resolved following a diagnosis of acute histoplasmosis. Years later, CT shows a well-defined, peripherally calcified histoplasmoma with satellite nodules, which subsequently underwent central liquefaction, cavitation, and the development of internal wall-adhering nodules on a follow-up scan.
Key takeaways
Histoplasmomas are typically stable, benign, calcified granulomatous nodules that represent a healed, dormant primary infection. However, in immunocompromised patients, such as those with chronic kidney disease or diabetes, these lesions can reactivate, undergo liquefaction necrosis, and cavitate, which may be entirely subclinical and discovered incidentally.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Intravascular Fat in the Pulmonary Artery (Intravascular Lipoma)Artifact
- Metastatic Lung Adenocarcinoma Presenting as a Hypervascular Superior Vena Cava MassNeoplastic
- Uncorrected Type 1 Truncus ArteriosusCongenital
- Pulmonary Interstitial Emphysema in Dermatomyositis-Associated Interstitial Lung Disease and Diffuse Alveolar DamageILD
- Traumatic Right Subclavian Artery-to-Vein Fistula and PseudoaneurysmTrauma
- Sinus Venosus Atrial Septal Defect and Partial Anomalous Pulmonary Venous Return with Eisenmenger SyndromeCongenital
- Overlying Hair and Deodorant/Talc Artifacts Mimicking Interstitial Lung Disease and CalcificationArtifact
- Catamenial Hemoptysis (Thoracic Endometriosis Syndrome)Other
See all cases from July 15, 2021 →