CTICasesDrug-Related Eosinophilic Pneumonia Secondary to Progesterone Preparation
Imaging findings
CT pulmonary angiography revealed bilateral, patchy, and strikingly peripheral subpleural consolidative opacities in both lungs. These findings were noted in a patient presenting with acute respiratory illness.
Key takeaways
Acute eosinophilic pneumonia can present with subpleural patchy consolidative opacities, often with a striking peripheral distribution. While frequently idiopathic, it can be drug-related. This case highlights a rare association with intramuscular progesterone preparations, where the active drug or excipients like sesame oil or benzyl alcohol may act as the antigen. Diagnosis is supported by peripheral eosinophilia and bronchoalveolar lavage findings, with resolution typically occurring upon withdrawal of the offending agent.
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