CTICasesGorham-Stout Disease (Generalized Lymphatic Anomaly) with Bony Anomalies
Imaging findings
The patient has scattered, unusual-looking sclerotic bony lesions in the sternum and ribs (chest CT not available in the transcript, but mentioned). An older study shows a large, multiloculated cystic collection in the left upper and lower abdomen. MRI reveals the L5 vertebral body is filled with a similar multiloculated cystic structure. The large lymphangioma in the bone required surgical correction.
Key takeaways
Gorham-Stout disease, or generalized lymphatic anomaly, is a rare condition characterized by the proliferation of lymphatic channels, often involving bone and soft tissues. It can lead to osteolysis ('vanishing bone disease') and present with multiloculated cystic lymphatic malformations. The bony anomalies are associated with lymphatic channels traversing the bones. Surgical intervention may be necessary for large or symptomatic lesions.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Complete Left Upper Lobe Atelectasis Due to Endobronchial Valves for EmphysemaArtifact
- Gastrobronchial FistulaIatrogenic
- Infected Aortic Graft with PseudoaneurysmVascular
- Left Atrial Myxoma with Variable Appearance on MRINeoplastic
- Thymic Carcinoma with Initial Regression and Subsequent Recurrence/GrowthNeoplastic
- Situs Inversus with Polysplenia and Bilateral Left-Sided Bronchial AnatomyCongenital
- Pleuroparenchymal Fibroelastosis (PPFE)ILD
- Mitral Valve Prolapse on Non-Gated CTVascular
See all cases from September 23, 2016 →
Related Congenital cases
- Large Coronary Artery Fistula from RCA to Right Atrium (Follow-up)
- Meandering Pulmonary Vein with Anomalous Connection to Right Innominate Vein
- Anomalous Left Main Coronary Artery Arising from RCA with Fistula to Coronary Sinus
- Bronchiectasis with Thin Bronchial Walls (Possible Williams-Campbell Syndrome or Sjogren's Phenotype)
- Congenital Lobar Overinflation Presenting with Spontaneous Pneumothorax in an Adult
- Anomalous Left Coronary Artery from Pulmonary Artery (ALCAPA) in an Asymptomatic Adult