CTICasesGiant Histoplasmosis Lymphadenopathy
Imaging findings
Chest CT in a patient from the Midwest shows giant, densely calcified mediastinal and hilar lymph nodes, representing old, healed histoplasmosis infection.
Key takeaways
Histoplasma capsulatum exposure is highly endemic in the Ohio and Mississippi River valleys. Healed infection can lead to massive, dense calcification of the mediastinal and hilar lymph nodes, which can compress adjacent bronchi or vessels.
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