CTICasesHistoplasmosis Lymphadenopathy with Milk of Calcium
Imaging findings
Chest radiograph shows massive, rim-calcified lymph nodes in the right hilum and a calcified parenchymal granuloma. The nodes have a calcified rim and lower-attenuation centers, representing milk of calcium/caseous necrosis from old histoplasmosis.
Key takeaways
Endemic fungal infections like histoplasmosis can lead to giant, exuberant calcification of hilar/mediastinal lymph nodes. These can show a rim-calcified appearance with central fluid/caseous material (milk of calcium).
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