CTICasesAmiodarone-Induced Systemic Deposition
Imaging findings
Non-contrast CT chest and upper abdomen demonstrates marked, diffuse hyperdensity of the liver, thyroid gland, and anterior chest wall skin. Mildly high-density consolidation is also noted in the right middle lobe and lingula, representing amiodarone-laden atelectatic lung.
Key takeaways
Amiodarone contains high concentrations of iodine, which accumulates in various body tissues and causes them to appear highly radiodense on non-contrast CT. Diffuse hyperdensity in the liver, skin, or thyroid reflects expected drug deposition and is not itself diagnostic of active, clinical drug-induced tissue toxicity.
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