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Lower Airway-Predominant COVID-19 Pneumonia

Imaging findings

Initial viral panels and nasal swabs were negative, but a subsequent swab was positive. CT chest demonstrates classic peripheral ground-glass opacities and consolidations in the lower lobes.

Key takeaways

The diagnostic sensitivity of nasopharyngeal swabs in COVID-19 is variable. In lower airway-predominant infection, the viral load in the nasopharynx may be low or absent, leading to initial false-negative tests. CT chest can be helpful to prompt isolation and repeat testing when clinical suspicion is high.

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