Ectopic Mediastinal Parathyroid Adenoma
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Imaging findings
Sestamibi scan with delayed images shows physiological uptake in the parotid and submandibular glands, along with an additional area of focal accumulation in the anterior mediastinum. This correlates to a hypervascular nodule on CT in the anterior mediastinum, which could be mistaken for a lymph node on non-contrast studies.
Key takeaways
Ectopic parathyroid adenomas are a common cause of persistent or recurrent hyperparathyroidism. Sestamibi scans, especially with SPECT/CT fusion, are highly effective in localizing these lesions, which often appear as hypervascular nodules in the anterior mediastinum.
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