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Mycoplasma-induced Acute Interstitial Pneumonia / ARDS

Mycoplasma-induced Acute Interstitial Pneumonia / ARDS▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A 47-year-old woman with acute hypoxia and dyspnea presented with diffuse lung disease on CT, characterized by peribronchial consolidation, reversed halo signs in the lower lobes, confluent ground-glass opacity, dependent consolidation, and subpleural sparing. Workup was largely negative except for positive IgG for Mycoplasma. Serial radiographs showed slow improvement.

Key takeaways

While typical Mycoplasma pneumonia often presents with lobar consolidation or bronchiolitis, this case suggests that Mycoplasma infection can induce a severe, delayed immune-mediated acute lung injury, resembling ARDS or acute interstitial pneumonia, potentially due to an aberrant post-infectious immune response.

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