CTICasesCoccidioidomycosis (Persistent Nodule)
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Imaging findings
Initial presentation with consolidation and adenopathy, along with surrounding small nodules, following a trip to Arizona. Post-treatment, a persistent central nodule with surrounding smaller nodules remained. The lesion was adjacent to the pleural space, causing chronic pleuritic pain.
Key takeaways
Coccidioidomycosis, or Valley Fever, is a fungal infection endemic to certain regions (e.g., Arizona). It can present with consolidation, adenopathy, and nodules. Residual infection can result in persistent nodules, which may be a source of chronic pain if adjacent to the pleura. Pathologically, Coccidioidomycosis is characterized by distinctive large spherules containing endospores, often within necrotic tissue surrounded by granulomatous inflammation, making it highly characteristic for diagnosis.
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