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Left Superior Vena Cava and Hemiazygos Continuation of the Inferior Vena Cava

Imaging findings

Chest radiograph demonstrates an indistinct aortic arch with a prominent vertical interface along the left superior mediastinum. CT chest and abdomen images show a persistent left superior vena cava (SVC) coexisting with a right SVC, draining into the right atrium via a dilated coronary sinus. Additionally, there is a hemiazygos continuation of the inferior vena cava (IVC) that courses superiorly and drains into the left SVC via the left superior intercostal vein, in a patient with abdominal heterotaxy (midline liver, right-sided stomach and spleen) but normal lung lobar anatomy.

Key takeaways

Persistent left SVC with hemiazygos continuation of the IVC is a rare congenital systemic venous anomaly that can produce a characteristic vertical stripe on frontal chest radiographs. Often associated with heterotaxy syndromes, this vascular anomaly represents a benign normal variant that is important to document for venous access planning and to prevent misinterpretation as a mediastinal mass.

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