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Metastatic Diffuse Large B-cell Lymphoma to the Lungs and Kidney

Metastatic Diffuse Large B-cell Lymphoma to the Lungs and Kidney▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A chest radiograph demonstrates a large mass-like area of opacity in the upper lung and numerous large, bilateral lung nodules. Chest CT confirms multiple large pulmonary nodules, some showing a conglomerate appearance with central low attenuation suggesting necrosis. A soft tissue mass is also visible arising from the right kidney.

Key takeaways

Secondary or metastatic diffuse large B-cell lymphoma to the lungs grows rapidly and mimics typical hematogenous metastatic disease, which carries a poor prognosis. This contrasts with primary pulmonary MALT lymphoma, which typically presents as slowly-progressing, ground-glass or consolidative lesions that characteristically contain air bronchograms.

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