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Radiation-Induced Ewing Sarcoma of the Chest Wall

Radiation-Induced Ewing Sarcoma of the Chest Wall▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A chest radiograph shows a well-circumscribed, posterior mass in the left upper hemithorax with destruction of the adjacent ribs. Chest CT demonstrates a large, destructive chest wall mass primarily involving and destroying the left upper ribs. Multivessel coronary artery calcification and premature atherosclerosis are also noted, likely secondary to prior radiation.

Key takeaways

This patient developed Ewing sarcoma of the chest wall in his 50s, decades after receiving chemoradiation therapy for childhood neuroblastoma in the left apex. Radiation-induced sarcomas and accelerated atherosclerosis are well-recognized long-term complications of thoracic radiation therapy.

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