Bronchiectasis and Tracheitis Associated with Ulcerative Colitis
Imaging findings
CT in a woman in her 60s with ulcerative colitis demonstrates diffuse bronchial wall thickening and bronchiectasis with airway caliber greater than the accompanying pulmonary artery (signet ring sign) throughout both lungs, along with extensive mucus plugging. The tracheal wall is also thickened. The findings are stable compared to a CT from five years prior.
Key takeaways
Inflammatory bowel disease (IBD), particularly ulcerative colitis, is associated with bronchopulmonary manifestations including bronchiectasis, constrictive bronchiolitis, and tracheitis. The airway disease may develop independently of the bowel disease activity, often years after the colitis. Ulcerative colitis-associated bronchiectasis may be severe and diffuse, and tracheal involvement is an unusual but documented feature. Drug-related lung injury should also be excluded in IBD patients on immunomodulatory agents.
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