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Sarcoidosis with Osseous Involvement

Imaging findings

Chest CT shows perilymphatic nodules in a bronchovascular distribution, mediastinal lymphadenopathy, and expiratory air trapping. Bone windows demonstrate multiple well-defined lytic lesions with narrow zones of transition in the thoracic spine and ribs. Patchy ground-glass opacity is also present, representing residual organizing pneumonia from recent COVID-19.

Key takeaways

Bone involvement is a rare manifestation of sarcoidosis, occurring in 1-13% of patients. It typically presents as lytic lesions with a narrow zone of transition, often in the hand bones, but can involve the spine and ribs, mimicking metastatic disease.

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