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Mediastinal Liposarcoma (Infiltrating)

Mediastinal Liposarcoma (Infiltrating)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Extensive fatty mass is seen infiltrating the mid and posterior mediastinum, encasing the aorta and extending along the posteromediastinal diaphragm. The mass contains lobules of soft tissue attenuation and areas of haziness, reflecting its infiltrating nature. Initial consideration for a complicated hernia was raised.

Key takeaways

Mediastinal liposarcomas can present as large, infiltrating fatty masses with variable soft tissue components. While some fatty mediastinal masses are benign, the presence of infiltrating features, non-fatty elements, and a patient's history of liposarcoma should raise strong suspicion for malignancy. This case emphasizes the importance of considering malignancy even in predominantly fatty lesions.

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