CTICasesPost-Transplant Lymphoproliferative Disorder (PTLD) Presenting as Airway-Centric Lung Nodules
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Imaging findings
Multiple well-defined, growing lung nodules, many of which are airway-centric and contain small air bronchograms. Abnormal soft tissue around the duodenum was also noted. Some small cysts and centrilobular emphysema are also present.
Key takeaways
Post-Transplant Lymphoproliferative Disorder (PTLD) should be considered in transplant patients presenting with growing lung nodules and extramedullary soft tissue abnormalities. Pulmonary PTLD can manifest as airway-centric nodules due to the lymphatic tissue distribution around airways. Diagnosis involves biopsy showing monoclonal lymphoproliferation, often EBV-positive.
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