CTICasesPanniculitis-like T-cell Lymphoma (Subcutaneous T-cell Lymphoma)
Imaging findings
CT and PET-CT in a patient with prior laryngectomy demonstrate diffuse infiltrating soft tissue stranding in the subcutaneous fat of the anterior chest wall and trunk without discrete abscess formation. PET shows diffuse hypermetabolic FDG uptake throughout the infiltrated subcutaneous fat, characteristic of a panniculitis-like distribution. Biopsy confirmed panniculitis-like T-cell lymphoma (CD8-positive cytotoxic T-cell type).
Key takeaways
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare CD8-positive cytotoxic T-cell lymphoma that infiltrates subcutaneous fat in a pattern mimicking panniculitis (lobular fat inflammation). CT shows diffuse infiltrating soft tissue density within subcutaneous fat without discrete abscess or rim enhancement. PET demonstrates diffuse hypermetabolic uptake throughout the affected subcutaneous fat. The diagnosis requires biopsy as the CT and PET appearances are non-specific.
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