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Small Cell Lung Cancer Interval Progression

Imaging findings

A patient presented with a new, innocuous-appearing cluster of small nodules/consolidation (Lung-RADS 2) which progressed to extensive metastatic small cell lung cancer within two months.

Key takeaways

Highly aggressive neuroendocrine tumors like small cell carcinoma can progress rapidly, making them notorious causes of "interval cancers" between screening studies.

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