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Adenocarcinoma Masquerading as Chronic Infection

Imaging findings

Persistent focal consolidation and reticulation in a smoker with underlying emphysema and fibrosis, initially attributed to recurrent infection due to positive sputum cultures. Serial imaging showed gradual expansion/filling-in, eventually confirmed as adenocarcinoma.

Key takeaways

In patients with underlying fibrosis, assume that persistent, focal, or progressive consolidations are malignant until proven otherwise, despite positive infectious workups.

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