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Left Isomerism with Polysplenia

Imaging findings

Chest and abdominal CT demonstrate heterotaxy syndrome characterized by left isomerism (polysplenia, multiple spleens on the right, midline pancreas, and reversed liver), azygos continuation of the inferior vena cava with a dilated azygos vein, and bilateral hyparterial bronchi.

Key takeaways

Heterotaxy syndrome with left isomerism is a congenital anomaly of lateralization. In contrast to right isomerism, left isomerism is more frequently associated with azygos continuation of the IVC and bilateral hyparterial bronchi, and patients often survive to adulthood asymptomatically.

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