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Fat Necrosis of Lipomatous Hypertrophy of the Interatrial Septum

Imaging findings

A patient with lipomatous hypertrophy of the interatrial septum and aortic and mitral valve disease underwent operative valve repair, during which the interatrial septum was cut. The post-operative CT shows a new peripheral rim of increased density around the still centrally fatty septum with a few internal striations, a change seen on both chest and abdominal imaging.

Key takeaways

Lipomatous hypertrophy of the interatrial septum that is surgically disrupted can undergo fat necrosis, producing a benign peripheral rim of higher attenuation (or enhancement/cyst-like change) around a fatty center, analogous to the classic appearance of fat necrosis elsewhere such as the breast. Recognizing this benign post-operative evolution avoids misinterpretation of the new peripheral density.

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