Fungal Infections: Cryptococcosis and Blastomycosis
Imaging findings
Cryptococcosis: Often presents as clustered, solid nodules that are perilymphatic rather than airway-centric, sometimes with cavitation. Blastomycosis: Presents as mass-like consolidation, stellate nodules (sometimes mimicking the "galaxy sign" of sarcoidosis), and non-healing cutaneous ulcers.
Key takeaways
Cryptococcus is an opportunistic infection often seen in immunocompromised patients, though it can occur in those with low-level risk factors like diabetes. Blastomycosis is environmentally acquired, particularly near waterways. It typically does not cause significant lymphadenopathy or pleural effusions, distinguishing it from histoplasmosis.
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