Post-Radiation Accelerated Atherosclerosis and Radiation Osteitis
Imaging findings
Frontal chest radiograph focusing on the left shoulder girdle of a patient treated with radiation therapy in the 1980s reveals dense, heavily calcified atherosclerotic plaques isolated to the left subclavian and axillary arteries. Concurrently, the regional bones demonstrate areas of rarefaction, irregular sclerosis, and soft tissue volume loss in the supraclavicular region.
Key takeaways
Radiation therapy can cause profound, localized chronic tissue changes decades after exposure. Key thoracic manifestations include accelerated, asymmetric atherosclerosis confined strictly to the radiation portal, chronic radiation-induced osteitis, and regional brachial plexopathy resulting from fibrotic remodeling.
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