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Giant Lymphocyte-Predominant Thymoma

Imaging findings

Chest CT demonstrates a massive, heterogeneous, lobulated soft tissue mass in the right hemithorax abutting the mediastinum and the medial pleura, accompanied by bilateral pleural effusions. The mass shows low-attenuation areas of necrosis and displacement of adjacent mediastinal structures.

Key takeaways

Giant thymomas can grow extensively into the pleural space, mimicking a primary pleural neoplasm like a solitary fibrous tumor of the pleura. Although most thymomas are located in the anterior mediastinum, they can occasionally present as massive eccentric masses. Histological classification, such as lymphocyte-predominant thymoma, is essential to guide oncological management.

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