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EVALI with Centrilobular Nodule Pattern

Imaging findings

CT chest in a young patient shows diffuse, symmetric centrilobular nodules and ground-glass opacities, with relative subpleural sparing. The patient reported vaping THC-containing e-cigarettes, and follow-up imaging showed complete resolution after vaping cessation.

Key takeaways

E-cigarette or Vaping Use-Associated Lung Injury (EVALI) has a wide spectrum of CT findings. While organizing pneumonia or lipoid pneumonia patterns are common, it can also present as diffuse centrilobular nodules representing acute bronchiolitis, which is highly reversible after cessation.

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