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Anti-Synthetase Syndrome (PL-12 Antibody)

Imaging findings

Extensive pulmonary opacities, lower lung predominance, and traction bronchiectasis. Pathologically, these showed cellular NSIP.

Key takeaways

In patients with connective tissue disease, look for specific clinical markers (e.g., Gottron papules). Lung biopsy is often unnecessary if serology confirms the syndrome.

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