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Minute Pulmonary Meningothelial-Like Nodules

Imaging findings

A middle-aged to older woman has numerous pure ground-glass nodules, biopsied on suspicion for multifocal adenocarcinoma and proven to be meningothelial-like nodules. The nodules are pure ground glass with smooth margins and are substantially larger than usually seen for this entity.

Key takeaways

Minute pulmonary meningothelial-like nodules are benign proliferations that appear as pure ground-glass nodules with smooth margins and can mimic multifocal adenocarcinoma, but unlike adenocarcinoma they are more uniform, do not distort the lung or incite a desmoplastic reaction, may show central umbilication, and are stable on old studies. They are typically small (often invisible on imaging despite being reported pathologically), so this case was atypical for its large nodule size; recognizing the entity avoids unnecessary biopsy.

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