CTICasesAML Lymphatic Blast Infiltration
Imaging findings
Chest CT shows severe bilateral interstitial lung edema (prominent septal lines, peribronchial fluid cuffing, and subpleural edema) associated with pleural effusions and mediastinal lymphadenopathy. Bone marrow biopsy confirmed acute myeloid leukemia (AML) with lymphatic blast infiltration.
Key takeaways
Leukemic infiltration of the pulmonary lymphatics in AML can mimic interstitial pulmonary edema or lymphangitic carcinomatosis. Identifying associated mediastinal/cardiophrenic lymphadenopathy can help guide the diagnosis.
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