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Marginal Zone Lymphoma in Sjögren's

Imaging findings

Serial chest CTs over three years show multiple pulmonary cysts, ground-glass opacities, and nodules that wax and wane in response to anti-inflammatory therapies. Biopsy confirmed marginal zone B-cell lymphoma (MALT lymphoma) in a patient with Sjögren's syndrome.

Key takeaways

Marginal zone lymphoma is a low-grade lymphoproliferative disorder associated with Sjögren's syndrome. The pulmonary lesions can wax and wane dynamically over time, mimicking an inflammatory process rather than a classic malignancy.

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