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Radiation-induced osteitis

Imaging findings

Chest CT in a breast cancer patient post-lumpectomy and radiation therapy shows extensive, exuberant periosteal new bone formation and hypertrophic bridging bone involving multiple adjacent ribs, associated with severe localized chest wall pain.

Key takeaways

Radiation-induced osteitis can present as chronic bone remodeling with hypertrophic, dense periosteal reaction and bridging osteophyte formation. This can mimic tumor recurrence but represents a benign radiation complication, which can cause significant pain.

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