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Metastatic melanoma

Imaging findings

Chest radiograph shows abnormal opacity in the subcarinal and right infra-hilar regions (the "no opacity zone" on lateral views), and CT confirms markedly enlarged, necrotic subcarinal and hilar lymph nodes causing mass effect on the bronchus intermedius. Biopsy confirmed metastatic melanoma.

Key takeaways

Metastatic melanoma can manifest as isolated, necrotic, and asymmetric mediastinal and hilar lymphadenopathy. On lateral radiographs, this presents as loss of the normal lucency behind the bronchus intermedius (the "no opacity zone"), mimicking other necrotic diseases like tuberculosis.

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