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Invasive Systemic Lymphoma

Imaging findings

Chest CT shows a rapidly enlarging, large cardiac mass invading the myocardium, associated with a pericardial effusion. Abdominal CT demonstrates progressive, bilateral diffuse infiltrative enlargement of the kidneys.

Key takeaways

High-grade systemic lymphomas can demonstrate rapid, aggressive multiorgan infiltration, presenting with cardiac masses, pericardial effusions, and diffuse nephromegaly over a period of weeks.

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