CTICasesJuvenile chronic arthritis-associated interstitial lung disease
Imaging findings
Serial chest CT scans over 16 years starting in early childhood show progressive lower lobe volume loss, reticulation, traction bronchiectasis, and esophageal dilatation, alongside scattered, thin-walled perivascular pulmonary cysts and centrilobular emphysema-like lucencies, in a young non-smoking woman with juvenile chronic arthritis.
Key takeaways
Juvenile chronic arthritis can rarely cause progressive interstitial lung disease in children and young adults. The imaging presentation is often a mixed pattern, containing features of non-specific interstitial pneumonia (basilar-predominant fibrosis) and lymphocytic interstitial pneumonia (cysts).
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