CTICasesSmoking-related diffuse lung disease
Imaging findings
Chest CT shows a complex combination of centrilobular emphysema, diffuse ground-glass opacity, poorly defined centrilobular nodules, subpleural cysts, and mild interstitial fibrosis in a middle-aged heavy smoker, without a classic pattern of pulmonary Langerhans cell histiocytosis or usual interstitial pneumonia.
Key takeaways
Heavy smoking can induce a heterogeneous spectrum of diffuse lung abnormalities that includes elements of respiratory bronchiolitis, desquamative interstitial pneumonia, emphysema, and interstitial fibrosis. A descriptive diagnosis is preferred when features are mixed.
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