CTICasesAdenocarcinoma Arising in a Lung Cyst
Imaging findings
Initial chest CT shows a stable, thin-walled cystic/cavitary lesion in the left upper lobe of a smoker. Over several years of follow-up, a thick soft tissue nodule develops along the inner wall of the cyst, which rapidly progresses to a large, aggressive adenocarcinoma.
Key takeaways
Lung adenocarcinomas can arise from the walls of pre-existing cysts or bullae. Any progressive wall thickening, nodular soft tissue formation, or enlargement of a cystic lesion should raise suspicion for malignancy.
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